Molten Salt Reactors (MSRs) are nuclear fission reactors in which either the fuel and/or the coolant is a molten salt. Molten salt is salt which liquifies at elevated temperatures and can store massive amounts of thermal energy at atmospheric pressure.
When used as fuel the molten salt is dissolved with fissile material. A fissile material is defined as one which is capable of fission (a reaction in which the nucleus of an atom splits into two to release energy). This happens after the nucleus is hit by either a high energy (fast) neutron or low energy (slow) neutron. Examples of fissile materials are uranium-235, plutonium-239 or uranium-233 that may be mixed with other fissionable material such as uranium-238.
Learn more about nuclear fission and energy.