Instructive Surfaces and Scaffolds for Tissue Engineering Using Radiation Technology. (Conducted Jointly with E31007)

Open for proposals

Project Type

Coordinated Research Project

Project Code

F23030

CRP

1965

Approved Date

13 September 2013

Status

3 - Active - Ongoing

Start Date

13 February 2014

Expected End Date

30 April 2019

Participating Countries

Bangladesh
China
Egypt
Malaysia
Poland
Portugal
Turkey
United States of America

Description

This CRP will support interested institutions in preparation and testing of instructive scaffolds and surfaces using radiation technology to create tissue grafts and help to decrease the need for human donors. It would also be considered as a forum for information, knowledge, and technology exchange among participating institutions and facilitate the formation of a network between the diverse disciplines involved. Radiation technologies plays a role in facilitating and accelerating the development of tissue engineering by addressing some of its challenges and opportunities, such as preparation/optimization of instructive scaffolds and their sterilization. The CRP is jointly conducted by the Division of Physical and Chemical Sciences (NAPC) and the Division of Human Health (NAHU). While NAPC will implement the part related to the development and testing of the instructive surfaces and scaffolds, NAHU will carry out the biomedical application part related to the end-uses of the instructive surfaces and scaffolds.

Objectives

is to engineer instructive scaffolds and surfaces using radiation technology to create tissues from autologous and allogeneic human somatic cells to provide tissue grafts and decrease the need for human donors.

Specific objectives

To bring together researchers from different research directions with end-users

To investigate and optimize the preparation of instructive scaffolds and surfaces

To investigate the use of radiation sterilization of the new instructive scaffolds and decellularized matrices

To study cell-cell-scaffold-matrix-ECM interaction

To study the possibilities and effectiveness of combining biological and non-biological materials on regeneration/repair

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