Instructive Surfaces and Scaffolds for Tissue Engineering Using Radiation Technology. (Conducted Jointly with E31007)
Open for proposals
Project Type
Project Code
F23030CRP
1965Approved Date
Status
Start Date
Expected End Date
Participating Countries
Description
This CRP will support interested institutions in preparation and testing of instructive scaffolds and surfaces using radiation technology to create tissue grafts and help to decrease the need for human donors. It would also be considered as a forum for information, knowledge, and technology exchange among participating institutions and facilitate the formation of a network between the diverse disciplines involved. Radiation technologies plays a role in facilitating and accelerating the development of tissue engineering by addressing some of its challenges and opportunities, such as preparation/optimization of instructive scaffolds and their sterilization. The CRP is jointly conducted by the Division of Physical and Chemical Sciences (NAPC) and the Division of Human Health (NAHU). While NAPC will implement the part related to the development and testing of the instructive surfaces and scaffolds, NAHU will carry out the biomedical application part related to the end-uses of the instructive surfaces and scaffolds.
Objectives
is to engineer instructive scaffolds and surfaces using radiation technology to create tissues from autologous and allogeneic human somatic cells to provide tissue grafts and decrease the need for human donors.
Specific objectives
To bring together researchers from different research directions with end-users
To investigate and optimize the preparation of instructive scaffolds and surfaces
To investigate the use of radiation sterilization of the new instructive scaffolds and decellularized matrices
To study cell-cell-scaffold-matrix-ECM interaction
To study the possibilities and effectiveness of combining biological and non-biological materials on regeneration/repair