Nanoscale Radiation Engineering of Advanced Materials for Potential Biomedical Applications

Closed for proposals

Project Type

Coordinated Research Project

Project Code

F23028

CRP

1537

Approved Date

9 September 2008

Status

Closed

Start Date

12 January 2009

Expected End Date

12 January 2013

Completed Date

21 May 2013

Description

There are critical needs for advanced materials in the area of biomaterial engineering primarily in generating biomaterials of enhanced specific functionalities improved biocompatibility, and minimal natural rejection but with enhanced inter facial adhesion. These can be achieved by introduction of proper functionalities at the nanoscale dimensions and radiation techniques are uniquely suited for such a task due to their favourable characteristics and in most cases, not possible by other methods of synthesis. Accordingly, many of the developing and developed Member States have an interest in creating advanced materials using a wide array of radiation sources and their broad expertise. In order to use the advantages of radiation techniques and address the needs of Member States for producing advanced materials for various health care applications, a CRP has been formulated based on the recommendations of a Consultant's Meeting. The CRP aims to support MS to develop methodologies for the use of radiation in the synthesis, modification, and characterization of nanomaterials - nanogels, nanoparticles, nanovehicles, nanoporous membranes, and surfaces with enhanced biocompatibility for potential biomedical applications, such as cell-sheet engineering and artificial tissue construction; diagnostics and imaging; drug delivery. Additionally, this CRP will facilitate net working between radiation technologists and biomedical scientists for the development of such applications

Objectives

The overall objective of this project was to support MS on the use of radiation in the synthesis, modification, and characterization of advanced materials by nanoscale control of their properties.

Specific objectives

To develop radiolytic methodologies for synthesis of nanoparticles and nanoporous membranes, as well as to synthesize and modify nanoparticle surfaces by attaching organic ligands.

To fabricate new stimuli-responsive surfaces by radiation induced grafting on the nanoscale for cell-sheet engineering with improved cell-matrix interactions and cell-function control.

To radiation synthesize polymeric, inorganic and hybrid nanocarriers, providing for controlled loading and improved releasing rate of drugs.

Impact

The CRP had very high impact on enhancing the research capabilities of the participating institutions in radiation engineering on the nanoscale, for the preparation/modification of new polymer materials intended for biomedical applications. The following achievements can be highlighted:

- nanogels and nanoparticles based on natural and/or synthetic polymers and proteins were developed by a precise control of the structure, size, shape and functionality;
- a number of developed nanocarriers were tested for drug delivery applications;
- nanoporous membranes were successfully fabricated, functionalized and tested for drug delivery;
- hydrogel-nanoparticle composites were developed for drug release, as drug-eluting coating for medical implant, and as coating with antimicrobial properties;
- multifunctional electrospun nanofiber network was produced and tested as sensor;
- functional thermo-responsive materials for cell sheet engineering have been prepared and successfully tested for culturing a cell monolayer.

Under this CRP several institutions succeeded in starting the transfer of technology to industry. The participants established numerous collaborations and signed relevant agreements between their institutions that will be in effect long after this CRP is completed. Participants have also used additional Agency support under national and regional TC projects to collaborate, and had also applied jointly for additional support of their work to various EU institutions. Additionally, the participants proposed several follow-up activities.

Relevance

The CRP is in line with research and development priorities of participating MS, and they expressed strong commitment for continued work in this area.

CRP Publications

Type

scientific paper

Year

2012

Description

Jovanovic, Z., Radosavljevic, A., Siljegovic, M., Bibic, N., Miskovic-Stankovic V., Kacarevic-Popovic, Z., “Structural and optical characteristics of silver/poly(N-vinyl-2-pyrrolidone) nanosystems synthesized by ?-irradiation”, Rad. Phys. Chem. 81 (2012) 1720-1728.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2009

Description

Bartoszek B, P. Ulanski, J. M. Rosiak; Radioliza impulsowa jako metoda do wyznaczania stalych szybkosci propagacji w polimeryzacji rodnikowej. 52. Zjazd Polskiego Towarzystwa Chemicznego oraz Stowarzyszenia Inzynierów i Techników Przemyslu Chemicznego, Lódz 12-16 September 2009

Country/Organization

Poland

Type

Patent

Year

2011

Description

BARSBAY, M., GUVEN, O., BESSBOUSSE, H., CLOCHARD, M-C, WADE, T., RAFT-mediated Radiation-induced Grafting of Acrylic acid from Track-etched PVDF Membranes to Develop Polymer Film Electrodes, Patent EP11306648.4 (deposited the 13th of nov. 2011).

Country/Organization

France - Turkey

Type

scientific meeting contribution

Year

2012

Description

Dadbin S, Akhavan, A. In Vitro enzymatic degradation of PLA/layered silicate nanocomposites, ISPST2012, Amirkabir University of Technology, Tehran, Iran, 21-25 October 2012

Country/Organization

Iran

Type

scientific paper

Year

2012

Description

Tajau, R. Adv. Mat. Res., 2012, 364, 278.

Country/Organization

Malaysia

Type

scientific conference contribution

Year

2011

Description

QUIROGA F. Y., GRASSELLI M.; Analysis of surface cationic microhydrogel structures by in situ fluorescence detection. 3rd South American Workshop & International Gregorio Weber Conference and Workshop on advance fluorescence techniques, Buenos Aires, Argentina, 12 - 17 December 2011.

Country/Organization

Argentina

Type

scientific conference contribution

Year

2012

Description

B. Beiler, M. Veres, L. Himics, M. Koós and Á. Sáfrány: Raman Spectroscopic Study on Porous Polymer Monoliths Prepared by Radiation Initiated Polymerization, 12th Tihany Symposium on Radiation Chemistry, August 27 – September 1, 2011, Zalakaros, Hungary (poster presentation).

Country/Organization

Hungary

Type

scientific paper

Year

2011

Description

S. Hasegawa, S. Takahashi, H. Iwase, S. Koizumi, N. Morishita, T. Narita, M. Ohnuma and Y. Maekawa, “Radiation-induced graft Polymerization of functional monomer into poly(ether ether ketone)film and structure-property analysis of the grafted membrane”, Polymer, 52, 98-106 (2011)

Country/Organization

Japan

Type

scientific paper

Year

2010

Description

CHEN, Q.D., SHEN, X.H., Formation of mesoporous BaSO4 microspheres with a larger pore size via Ostwald ripening at room temperature, Cryst. Growth Des. 10 (2010) 3838.

Country/Organization

China

Type

scientific paper

Year

2010

Description

BISWAL, J., RAMNANI, S. P., SHIROLIKAR, S., SABHARWAL, S., “Seedless synthesis of gold nanorods employing isopropyl radical generated using gamma radiolysis technique”, Int. J. Nanotechnol. 7 (2010) 907.

Country/Organization

India

Type

scientific meeting contribution

Year

2012

Description

Dadbin S, Ahmadian V. Crystallinity of PLA/HAP nanocomposites: effect of gamma irradiation, ISPST2012, Amirkabir University of Technology, Tehran, Iran, 21-25 October 2012

Country/Organization

Iran

Type

scientific paper

Year

2013

Description

MISRA, N., KUMAR, V., BORDE, L. AND VARSHNEY, L.; Localized surface plasmon resonance-optical sensors based on radiolytically synthesized silver nanoparticles for estimation of uric acid, Sensors and Actuators B: Chemical, 178 (2013), 371-378.

Country/Organization

India

Type

scientific paper

Year

2011

Description

Tajau, R. J. Nuc. And Rel. Tech., 2011, 8, 6.

Country/Organization

Malaysia

Type

scientific paper

Description

Soto Espinoza, S. L., Arbeitman, C. R., Clochard, M.C and Grasselli M.; Functionalization of nanochannels by radiation-induced grafting polymerization on PET track-etched membranes, Radiat. Phys. Chem. (submitted for publication)

Country/Organization

Argentina

Type

scientific paper

Year

2011

Description

BISWAL, J., RAMNANI, S. P., SHIROLIKAR , S., SABHARWAL S., “Synthesis of rectangular plate like gold nanoparticles by insitu generation of seeds by combining both radiation and chemical methods”, Radiat. Phys. Chem. 80 (2011) 44.

Country/Organization

India

Type

scientific paper

Year

2010

Description

YANG, S.G., CHEN, Q.D., SHI, J.F., SHEN, X.H., Controllable radiolytic reduction of Cu2+ in aqueous solution by ß-cyclodextrin, Acta Phys.-Chim. Sin. 26 (2010) 805. (in Chinese)

Country/Organization

China

Type

scientific meeting contribution

Year

2009

Description

Kadlubowski S, R. Czechowska-Biskup, P. Ulanski, J. M. Rosiak; Inicjowana radiacyjnie synteza nanozeli polimerowych, III Krajowa Konferencja Nanotechnologii - nano2009, Warszawa (Poland); 22-26 June 2009

Country/Organization

Poland

Type

scientific paper

Year

2012

Description

K. Enomoto, S. Takahashi and Y. Maekawa, “Novel Characterization Method for Graft Polymer Structures Chemically Attached on Thermally Stable Polymer Films”, Macromol. Chem. Phys., 213, 72-78 (2012)

Country/Organization

Japan

Type

scientific meeting contribution

Year

2012

Description

Krstic, J., Spasojevic, J., Radosavljevic, A., Kacarevic-Popovic, Z., „Non-isothermal kinetics of dehydratation of Ag/PVA hydrogel nanocomposite synthesized by g-irradiation“, 11th International Conference on Fundamental and Applied Aspects of Physical Chemistry, PHYSICAL CHEMISTRY 2012, Belgrade, Serbia, Septembar 24-28, 2012, Proceedings, Volume I, C-20-P, 212-214.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2009

Description

SMOLKO, E. E., BRITOS, C.N., CARBAJAL, M.L., HIDALGO, R., SOTO ESPINOZA, S., QUIROGA, F., TRELLES, J.A., GRASSELLI, M.; Radiation-induced grafting of porous polymers for biological applications, Latin American Section of the American Nuclear Society (LAS/ANS) . Symposium on “Integration of Nuclear Technologies in Latin America". Argentina, Jun 23 – 26, 2009.

Country/Organization

Argentina

Type

scientific conference contribution

Year

2011

Description

Gopalan A., Kyung Ryeol Ko, Se-Hee Lee, Komathi S., Miklos Veres, Kwang-Pill Lee, “ Radiation induced preparation of new multifunctional nanobiowebs”, 12th Tihany Symposium on Radiation Chemistry, August 27 – September 1, 2011, Zalakaros, Hungary (poster presentation).

Country/Organization

Hungary and Korea, Rep of

Type

scientific paper

Year

2012

Description

Hamzah, Y.; Yunus, W.; N.M. Isa,; Tajau R,; Hashim, K. e-Polymers, 2012, no. 045.

Country/Organization

Malaysia

Type

scientific paper

Year

2012

Description

WALO, M., PRYZBYTNIAK, G., KAVAKLI, A. P., GÜVEN, O., “Radiation-induced Graft Polymerization of N-vinyl pyrrolidone onto Segmented Polyurethane Based on Isophorone Diisocyanate”, Rad. Phys. Chem., 82(2012)xxx.

Country/Organization

Turkey

Type

scientific conference contribution

Year

2012

Description

MISRA, N., BISWAL, J., SABHARWAL, S., VARSHNEY, L.; Colorimetric estimation of trace levels of hydrogen peroxide using radiolytically synthesized Gold nanoparticles, ICWNCN, Delhi University, New Delhi, India, 13-16, March 2012.

Country/Organization

India

Type

scientific paper

Year

2012

Description

MISRA, N., BISWAL, J., GUPTA, A., SAINIS J, K.,. SABHARWAL, S., “Gamma radiation induced synthesis of gold nanoparticles in aqueous polyvinyl pyrrolidone solution and its application for hydrogen peroxide estimation” Radiat. Phys. Chem. 81 (2012) 195.

Country/Organization

India

Type

scientific paper

Year

2011

Description

T. Yamaki, N. Nunung, H. Koshikawa, M. Asano, S. Sawada, S. Hasegawa, Y. Maekawa, K.-O. Voss, C. Trautmann and R. Neumann, “Conductometric Analysis for the Formation of Poly(vinylidene fluoride)-Based Ion Track Membranes”, ECS Trans., 35, 1-12 (2011)

Country/Organization

Japan

Type

scientific conference contribution

Year

2009

Description

KRKLJES, A., KACAREVIC-POPOVIC, Z., NEDELJKOVIC, J., „Radiolytic synthesis and characterization of thermoresponsive Ag/PNIPA hydrogel nanocomposites“, 2nd International Conference of Physics of Optical Materials and Devices ICOM 2009, Herceg Novi, Montenegro, August 26-31, 2009, Book of Abstract, p.177.

Country/Organization

Serbia

Type

scientific meeting contribution

Description

KrstiC J., KrkljeS, A., MitriC, M., KaCareviC-PopoviC, Z., “Characterization and swelling kinetics of Ag/PVA hydrogel nanocomposites synthesized by ?-irradiation”, International Workshop on Processing of Nanostructured Ceramics, Polymers, and Composites, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia, November 29-30, 2010, Book of Abstracts, Poster-P4, p.48.

Country/Organization

Serbia

Type

scientific paper

Description

Hassan A. Abd El-Rehim , El-Sayed A. Hegazy , Ashraf A. Hamed , Ahmed E. Swilem, Controlling the Size and Swellability of Stimuli-Responsive Poly(vinylpyrrolidone)/Poly(acrylic acid) (PVP/PAAc) Nanogels Synthesized by Gamma Radiation-Induced Template Polymerization, European Polymer Journal, Submitted for publication (2012).

Country/Organization

Egypt

Type

scientific meeting contribution

Year

2012

Description

Krstic, J., Spasojevic, J., Radosavljevic, A., Kacarevic-Popovic, Z. M., „Gamma irradiation technique for plasmonic nanoengineering of Ag/hydrogels nanocomposites“, The 3rd International Conference On The Physics Of Optical Materials And Devices, Belgrade, Serbia, September 3-6,2012, Proceedings, P2.1-31, 240.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2012

Description

KUMAR,V., GOEL, N. K., FRANCIS, S., BHARDWAJ, Y. K., VARSHNEY, L.; Hybrid Organic/Inorganic nanocomposite coating by electron beam curing process, Thermans, Mumbai, India, 31st January-2nd February 2012.

Country/Organization

India

Type

scientific paper

Year

2012

Description

Hamzah, Y.; Yunus, W.; N.M. Isa, Pertanika J. Sci. & Technol.,2012, 20, 401

Country/Organization

Malaysia

Type

scientific paper

Year

2013

Description

Biswal, J., Singh,S., Rath, M. C., Ramnani S. P., Sabharwal, S., „Synthesis of CdSe quantum dots in PVA matrix by radiolytic methods”, Int. J. Nanotechnol., 7(2010) 1013- 126N. Misra,V. Kumar, L. Borde, L. Varshney, Localized surface plasmon resonance-optical sensors based on radiolytically synthesized silver nanoparticles for estimation of uric acid, Sensors and Actuators B: Chemical, 2013, 178, 371-378.

Country/Organization

India

Type

scientific meeting contribution

Year

2012

Description

Sistemas avanzados de administración de medicamentos - Instituto de Ciencias Nucleares, UNAM, Mexico City, Mexico. (2012) Invited Talk “Computational tools applied to the development of protein-based drug carriers” – Gustavo H. C. Varca

Country/Organization

Brazil

Type

scientific conference contribution

Year

2011

Description

SANCHEZ, M.L., SOTO ESPINOZA, S.L., QUIROGA, F.Y., CARBAJAL, M.L., GRASSELLI, M.; Procesos de modificación superficial de polímeros mediante radiación gamma, II Workshop de Transferencia de Tecnología en el Área de Materiales. Mar del Plata, Argentina. 28 - 30 November 2011

Country/Organization

Argentina

Type

scientific conference contribution

Year

2009

Description

Dispenza, M.A. Sabatino, D. Bulone, D. Giacomazza, G. Ghersi, M. Leone, S. Rigogliuso, G. Spadaro “Macromolecular engineering of hydrogels: from macro to nano scalar materials for different levels of biointeraction” Polymerfest, Palermo August 30 – September 02, 2009, p 237-238.

Country/Organization

Italy

Type

scientific paper

Year

2010

Description

CHEN, Q.D., SHEN, X.H., GAO, H.C., Radiolytic syntheses of nanoparticles in supramolecular assemblies, Adv. Colloid Interface Sci. 159 (2010) 32. (Invited review)

Country/Organization

China

Type

scientific paper

Year

2010

Description

S. Sawada, T. Yamaki, T. Ozawa, A. Suzuki, T. Terai, and Y. Maekawa, “Structural analysis of radiation-grafted polymer electrolyte membranes by dissipative particle dynamics simulation”, Kobunshi Ronbunshu, 67, 224-227(2010) (in Japanese)

Country/Organization

Japan

Type

scientific conference contribution

Year

2012

Description

SOTO ESPINOZA, S. L., GRASSELLI, M.; Análisis fluorométrico de nanoinjertos en membranas de poros perfectos, Encuentro Superficie y Materiales Nanoestructurados. La Falda, Argentina, 16 - 18 de May 2012.

Country/Organization

Argentina

Type

scientific paper

Year

2010

Description

MOMESSO R G.R.A., MORENO C.S., ROGERO S.O., ROGERO J.R., SPENCER P.J.,LUGAO A.B. Radiation stability of resveratrol in immobilization on poly vinyl pyrrolidone hydrogel dressing for dermatological use. Radiation Physics and Chemistry, Volume 79, Issue 3, March 2010, Pages 283-285

Country/Organization

Brazil

Type

scientific paper

Year

2010

Description

KACAREVIC-POPOVIC, Z., DRAGASEVIC, M., KRKLJES, A., POPOVIC, S., JOVANOVIC, Z., TOMIC, S., MISKOVIC-STANKOVIC, V., “On the Use of Radiation Technology for Nanoscale Engineering of Silver/Hydrogel Based Nanocomposites for Potential Biomedical Application”, The Open Conference Proceedings Journal 1 (2010) 200-206.

Country/Organization

Serbia

Type

scientific meeting contribution

Year

2009

Description

Rokita B., P. Komorowski, P. Ulanski, B.Walkowiak, J.M. Rosiak; Wplyw ultradzwieków na kwas deoksyrybonukleinowy - DNA, 52. Zjazd Polskiego Towarzystwa Chemicznego oraz Stowarzyszenia Inzynierów i Techników Przemyslu Chemicznego, Lódz 12-16 September 2009

Country/Organization

Poland

Type

scientific paper

Year

2011

Description

Dadbin S, Naimian F, Akhavan A. Poly(Lactic acid)layered Silicate nanocomposite films: morphology, mechanical properties and effects of ?-radiation J Appl Polym Sci 2011; 122: 142-149.

Country/Organization

Iran

Type

scientific paper

Year

2012

Description

Gopalan A., Kyung Ryeol Ko, Se-Hee Lee, Komathi S., Miklos Veres, Kwang-Pill Lee, “Radiation induced preparation of new multifunctional nanobiowebs”, Radiation Physics and Chemistry 81 (2012) 1407–1410

Country/Organization

Korea, Rep of

Type

scientific conference contribution

Year

2012

Description

M. Veres, L. Himics, S. Tóth, K.-P. Lee, A.I. Gopalan, M. Koós, Nanodiamond-Polymer Composites Prepared by Gamma Radiation Initiated Free Radical Polymerization, International Conference on Diamond and Carbon Materials, 3-6 September, 2012, Granada, Spain (poster presentation).

Country/Organization

Hungary

Type

scientific conference contribution

Year

2012

Description

QUIROGA F. Y., GRASSELLI, M.; Síntesis y caracterización de una red catiónica injertada en HDPE para promover la adsorción de microrganismos, XII Encuentro Superficie y Materiales Nanoestructurados. La Falda, Argentina, 16 - 18 May 2012.

Country/Organization

Argentina

Type

scientific meeting contribution

Year

2011

Description

KrstiC, J., SpasojeviC, J., KrkljeS, A., KaCareviC-PopoviC, Z., “Swelling kinetics and antimicrobial activity of radiolytically synthesized nano-Ag/PVA hydrogels”, 12th Tihany Symposium on Radiation Chemistry, Zalakaros, Hungary, August 27 - September 1, 2011, Program and Abstracts, p.110.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2011

Description

K-P Lee, Se-Hee Lee, S. Komathi, Gopalan A. “ Preparation of Co/Pd alloy particles dispersed multiwalled carbon nanotube supported nanocatalysts via gamma irradiation”, 12th Tihany Symposium on Radiation Chemistry, August 27 – September 1, 2011, Zalakaros, Hungary (poster presentation).

Country/Organization

Korea, Rep of

Type

scientific conference contribution

Year

2010

Description

KRSTIC, J., KRKLJES, A., KACAREVIC-POPOVIC, Z., „Swelling Behavior of Ag/PVA hydrogel nancomposite synhesized by .?-irradiation“, 10th International Conference of Fundamental and Applied Aspects of Physical Chemistry, PHYSICAL CHEMISTRY 2010, September 21-24, 2010, Belgrade, Serbia, Proceedings, p.110-112.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2009

Description

KRKLJES, A., KACAREVIC-POPOVIC, Z., NEDELJKOVIC, J., „The Influence of Network Parameters on the Properties of Thermoresponsive Ag/PNIPA Hydrogel Nanocomposite Synthesized by Gamma Irradiation“, 11th Annual Conference YUCOMAT 2009, Herceg Novi, Montenegro, August 31 - September 4, 2009, Programme and The Book of Abstracts, P.S.D.9, p.176.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2011

Description

QUIROGA F. Y., LELES DA SOUZA, A., LAMEIRAS F.S., GRASSELLI M.; Microhidrogeles catiónicos injertados sobre HDPE : síntesis, caracterización físicoquímica y estudios funcionales en la adsorción de Escherichia coli. XL Reunión Anual de la Sociedad Argentina de Biofísica. Buenos Aires, Argentina, 5 – 7 December 2011

Country/Organization

Argentina

Type

scientific paper

Year

2010

Description

CVETICANIN, J., KRKLJES, A., KACAREVIC-POPOVIC, Z., MITRIC, M., RAKOCEVIC, Z., TRPKOV, DJ., NESKOVIC, O., “Functionalization of carbon nanotubes with silver clusters”, Appl. Surf. Sci. 256 (2010) 7048-7055.

Country/Organization

Serbia

Type

scientific meeting contribution

Year

2009

Description

Rokita B., P. Komorowski, P. Ulanski, B. Walkowiak, J. M. Rosiak; Sonolysis of DNA from calf thymus in aqueous solution, 4th European Young Investigators Conference, Collegium Polonicum, Slubice (Poland); 18 - 21 June 2009

Country/Organization

Poland

Type

scientific meeting contribution

Year

2009

Description

Ulanski P.; Radiation chemistry of polymers - some opportunities and trends, Radiation Chemistry in the 21st Century A Visionary Meeting, University of Notre Dame, Notre Dame,Indiana, USA, 12 – 15 July 2009

Country/Organization

Poland

Type

scientific paper

Description

Hassan A. Abd El-Rehim , Anke Klingner , El-Sayed A. Hegazy, Ashraf A. Hamed, Ahmed E. Swilem, Developing the Potential Ophthalmic Applications of Pilocarpine Entrapped Into Poly(vinylpyrrolidone)/Poly(acrylic acid) (PVP/PAAc) Nanogel Dispersions Prepared By Gamma Radiation, Biomacromolecules, submitted for publication 2012

Country/Organization

Egypt

Type

scientific conference contribution

Year

2009

Description

Dispenza, G. Spadaro “Nuovi materiali nanocompositi a base di idrogeli e polimeri conduttori per l’elettronica molecolare” III Workshop nazionale AICING, Genova 14-16 giugno 2009. K3 (Keynote).

Country/Organization

Italy

Type

scientific paper

Description

Dadbin S, Naimian F. Poly (lactic acid)/Hydroxyapatite Bio-nanocomposites: Effects of gamma irradiation and composition on crystallinity, mechanical properties, morphology and enzymatic degradation, submitted to Polymer International

Country/Organization

Iran

Type

scientific paper

Description

PASANPHAN, W., CHOOFONG, S., RIMDUSIT, P., “Deoxycholate-chitosan nanosphere fabricated by g-irradiation and chemical modification: nanoscale synthesis and controlling studies”, J. Appl. Polym. Sci. (2010) Revision.

Country/Organization

Thailand

Type

scientific conference contribution

Year

2010

Description

9th Ionizing Radiation and Polymer Symposium – Maryland , US. (2010) Oral Presentation - “Gamma Irradiation Effects over papain activity in different media” - Varca, G.H.C; Paiffer, F.; Mathor, M.B.; Kaneko, T.M.; Rogero, S.O.; Lopes, P.S.; Lugão, A.B.

Country/Organization

Brazil

Type

scientific paper

Year

2010

Description

ATES, Z., GÜVEN, O., Radiation-induced Molecular Imprinting of D-glucose ontoPoly(2-hydroxyethyl methacrylate) Matrices Using various Crosslinking Agents, Rad. Phys. Chem, 79(2010)219-222.

Country/Organization

Turkey

Type

scientific meeting contribution

Year

2009

Description

PASANPHAN, W.*, RIMDUSIT, P., CHOOFONG, S., CHIRACHANCHAI, S., Chirachanchai. “Chitosan nanoparticle formation: systematic condition based on gamma irradiation and chemical modification studies.” The 6th European Conference on Marine Natural Products, Porto, Portugal, 17-24 July 2009

Country/Organization

Thailand

Type

Master Degree Thesis

Year

2012

Description

Ahmed E. Swilem, Radiation Synthesis of Nano – scale Materials For Biomedical Applications, Master Degree Thesis, Faculty of Science, Ain Shams University, 2012

Country/Organization

Egypt

Type

scientific conference contribution

Year

2009

Description

GRASSELLI, M., BRITOS, C.N., CARBAJAL, M.L., HIDALGO, R., SOTO ESPINOSA, S.L., QUIROGA, F., TRELLES, J.A., SMOLKO, E.E.; Radiation- Induced grafting of porous polymers for biological applications. V Argentine-Chilean Polymer Symposium. VIII Argentine Polymer Symposium. IX Chilean Symposium of Polymer Chemistry and Physical-Chemistry. 18-21 Octubre 2009. Los Cocos, Córdoba, Argentina.

Country/Organization

Argentina

Type

scientific meeting contribution

Year

2010

Description

Rida, W.M.Z.W. Yunus, Y. Hamzah, K.Z.M. Dahlan, M.H. Mahmood, “Radiation Synthesis Of Micro-Nano Particle Of Acrylated Palm Oil”, Fundamental Science Congress, Universiti Putra Malaysia, Serdang, Malaysia, Oral presentation, May 2010.

Country/Organization

Malaysia

Type

scientific paper

Year

2010

Description

N. Nunung, T. Yamaki, H. Koshikawa, M. Asano, K. Enomoto, S. Sawada, Y. Maekawa, K.-O. Voss, C. Trautmann and R. Neumann, “Poly(vinylidene fluoride)-based ion track membranes with different pore diameters and shapes: SEM observations and conductometric analysis“, Electrochemistry, 78, 146-149 (2010)

Country/Organization

Japan

Type

scientific paper

Year

2012

Description

Soto Espinoza, S. L., Sánchez, M. L., Risso, V., Smolko, E. E. and Grasselli M.; Radiation Synthesis of Seroalbumin Nanoparticles, Radiat. Phys. Chem. 81 (2012) 1417–1421.

Country/Organization

Argentina

Type

scientific conference contribution

Year

2011

Description

M. Veres, L. Himics, S. Tóth, K.-P. Lee, A. Gopalan, M. Koós: Surface Functionalization of Nanocrystalline Diamond Using Free Radical Polymerization, 22nd European Conference on Diamond, Diamond-like Materials Carbon Nanotubes and Nitrides, 4-8 September, 2011, Garmisch-Paterkirchen, Germany (poster presentation).

Country/Organization

Hungary

Type

scientific paper

Year

2010

Description

BISWAL, J., RAMNANI, S. P., TEWARI, R., DEY G, K., SABHARWAL, S., “Short aspect ratio gold nanorods prepared using gamma radiation in the presence of Cetyltrimethyl ammonium bromide (CTAB) as a directing agent”, Radiat. Phys. Chem. 28 (2010) 441.

Country/Organization

India

Type

scientific paper

Year

2012

Description

ALCÂNTARA M.T.S.,. BRANT A.J.C, GIANNINI D.R., PESSOA J.O.C.P., ANDRADE A.B., RIELLA H.G.,. LUGAO A.B. Influence of dissolution processing of PVA blends on the characteristics of their hydrogels synthesized by radiation—Part I: Gel fraction, swelling, and mechanical propertiesRadiation Physics and Chemistry, Volume 81, Issue 9, September 2012, Pages 1465-1470.

Country/Organization

Brazil

Type

scientific conference contribution

Year

2012

Description

CASAJÚS, G., SOTO ESPINOZA, S. L. SMOLKO E.E. GRASSELLI, M.; Síntesis de nanopartículas de proteína mediante radiación ionizante de 60Co, XII Encuentro Superficie y Materiales Nanoestructurados. La Falda, Argentina, 16 - 18 May 2012.

Country/Organization

Argentina

Type

scientific paper

Year

2012

Description

OLIVEIRA M.J.A., AMATO V.S., LUGAO A.B., PARRA D.F.. Hybrid hydrogels produced by ionizing radiation technique. Radiation Physics and Chemistry, Volume 81, Issue 9, September 2012, Pages 1471-1474.

Country/Organization

Brazil

Type

scientific conference contribution

Year

2009

Description

Bartoszek N, P. Ulanski, J. M. Rosiak; Free-radical reactions involving macromolecules as studied by pulse radiolysis - factors influencing reaction rate constants, 4th European Young Investigators Conference, Collegium Polonicum, Slubice (Poland); 18 - 21 June 2009

Country/Organization

Poland

Type

scientific paper

Year

2012

Description

CvetiCanin, J., Koteski, V., BeloseviC-Cavor, J., RadosavljeviC, A., KaCareviC-PopoviC, Z., Trpkov, DJ., ACimoviC, D., RogiC MiladinoviC, Z., CindriC, M., NeSkoviC O., “MALDI TOF and theoretical investigation of silver clusters obtained by gamma irradiation”, Vacuum 89 (2012) 47-52.

Country/Organization

Serbia

Type

scientific paper

Year

2012

Description

K-P Lee, Se-Hee Lee, S. Komathi, Gopalan A. “ Preparation of Co/Pd alloy particles dispersed multiwalled carbon nanotube supported nanocatalysts via gamma irradiation” Radiation Physics and Chemistry 81 (2012) 1422–1425

Country/Organization

Korea, Rep of

Type

scientific conference contribution

Year

2009

Description

Dispenza, M.A. Sabatino, A. Niconov, E. Caponetti, R. Matassa, G. Navarra, S. Piazza, G. Spadaro “Biocompatible polyaniline nanocomposites build a soft interface between biology and opto-electronics” Polymerfest, Palermo August 30 – September 02, 2009. P 223-224

Country/Organization

Italy

Type

scientific conference contribution

Year

2012

Description

MISRA, N., KUMAR, V., VARSHNEY, L.; Silver nanoparticles based optical biosensors for estimation of uric acid, ISMC, TSH, Mumbai, India, 11-15 December 2012, (Best Poster Award).

Country/Organization

India

Type

scientific paper

Year

2010

Description

PASANPHAN, W.*, RIMDUSIT, P., CHOOFONG, S., PIROONPAN, T., NILSUWANKOSIT, S., “Systematic fabrication of chitosan nanoparticle by gamma irradiation”, Radiat. Phys. Chem., 79 (2010) 1095–1102.

Country/Organization

Thailand

Type

scientific paper

Year

2010

Description

Dispenza, M. Ricca, C. LoPresti, G Battaglia, M. La Valle, D. Giacomazza, D. Bulone “E-beam irradation and UV photocrosslinking of microemulsion-laden poly(N-vinyl-2-pyrrolidone) hydrogels for “in-situ” encapsulation of volatile hydrophobic compounds”, Polymer Chemistry, (2010) DOI: 10.1039/c0py00161a.

Country/Organization

Italy

Type

scientific meeting contribution

Year

2012

Description

Spasojevic, J., Krstic, J., Radosavljevic, A., Kalagasidis-Krucsic, M., Kacarevic-Popovic, Z., „Poly(NiPAAm-co-IA) hydrogels synthesized by g-irradiation: Swelling behavior in water“, 11th International Conference on Fundamental and Applied Aspects of Physical Chemistry, PHYSICAL CHEMISTRY 2012, Belgrade, Serbia, Septembar 24-28,2012, Proceedings, Volume II, J-12-P, 550-552.

Country/Organization

Serbia

Type

scientific paper

Year

2012

Description

K. Enomoto, S. Takahashi, R. Rohani, Y. Maekawa, “Synthesis of Copolymer Grafts Containing Sulfoalkyl and Hydrophilic Groups in Polymer Electrolyte Membranes”, J. Membr. Sci., 415–416, 36–41 (2012)

Country/Organization

Japan

Type

scientific conference contribution

Year

2012

Description

International Conference on Protein Stabilization – Prostab2012 Lisbon, Portugal. (2012) Oral presentation - “ Stabilization of Papain by cyclic oligosaccharides: influence of B-CD and B-derivatives over the biological properties of papain” - Varca, G.H.C; Ferraz, C.C; Esteves-Pedro, N.M.; Lopes, P.S.; Mathor, M.B.; Lugão, A.B.

Country/Organization

Brazil

Type

scientific conference contribution

Year

2013

Description

FRANCIS, S., NUWAD, J., GUPTA, A., SAINIS, J. K., MITRA, D., VARSHNEY , L.; Gamma radiolytic synthesis of gold nanoplates in presence of polydiallyldimethylammoniumchloride as the capping agent NSRP, Meghalaya, India. 20-22, March 2013.

Country/Organization

India

Type

scientific conference contribution

Year

2012

Description

Hoffman, A.S., “Evolution of Biomaterials into the Nano-Era” plenary talk, 10th meeting of the Ionizing Radiation and Polymers (IRaP2012) Symposium, Krakow, Poland, 14-19 October 2012, Book of Abstracts, pp. 16.

Country/Organization

USA

Type

scientific conference contribution

Year

2012

Description

FRANCIS, S. TEWARI, R. MITRA, D. VARSHNEY, L.; Gold nanoplate synthesis by hydrogen peroxide reduction of gold chloride, ISMC, Mumbai, India, 11-15, December 2012.

Country/Organization

India

Type

Patent

Year

2011

Description

European Patent 2011DI0057 issued in the names of Haad Besbousse, Travis Wade, Marie-Claude Clochard, Murat Barsbay and Olgun Güven on “RAFT-mediated Radiation-induced Grafting of Acrylic acid from Track-etched PVDF Membranes to Develop Polymer Film Electrodes”

Country/Organization

France - Turkey

Type

scientific meeting contribution

Year

2009

Description

Ulanski P., S. Kadlubowski, J.K Jeszka, J.M. Rosiak; Synthesis of nanogels by radiation-induced intramolecular crosslinking of single polymer chains, Workshop on Progress in Bio- and Nanotechnology, Lodz, Poland; 12-14 February 2009

Country/Organization

Poland

Type

scientific paper

Year

2011

Description

K. Enomoto, S. Takahashi, T. Yamashita and Y. Maekawa, “Degradation manner of polymer grafts chemically attached on thermally stable polymer films: swelling-Induced detachment of hydrophilic grafts from hydrophobic polymer substrates in aqueous media“, J. Mater. Chem., 21, 9343-9349 (2011)

Country/Organization

Japan

Type

scientific meeting contribution

Year

2009

Description

RIMDUSIT, P., PASANPHAN, W.*, “Gamma-ray generated chitosan nanoparticle: systematic preparation study”, The 7th Eco-Energy and Materials Science and Engineering Symposium, Chiangmai, Thailand, 19-22 November 2009, International Proceeding 131-135.

Country/Organization

Thailand

Type

scientific meeting contribution

Year

2009

Description

CHOOFONG, S., PASANPHAN, W.* “Particle size lowering of chitosan nanosphere by gamma irradiation and chemical modification”, The 7th Eco-Energy and Materials Science and Engineering Symposium, Chiangmai, Thailand, 19-22 November 2009, International Proceeding 125-130.

Country/Organization

Thailand

Type

scientific conference contribution

Year

2010

Description

KRSTIC, J., KRKLJES, A., PERIC-GRUJIC, A., MITRIC, M., KACAREVIC-POPOVIC, Z., „Hybrid Ag/PVA hydrogel nanocomposites for potentional biomedical application synthesized by gamma irradiation“, X International Conference on Nanostructured Materials NANO 2010, Rome, Italy, September 13-17, 2010, Abstracts book, Poster-Th-98, p.191.

Country/Organization

Serbia

Type

scientific conference contribution

Year

2012

Description

Latin American Congress on Biomaterials – Natal, Brazil. (2012) “Radio-induced protein reticulation for biomedical purposes” – Invited Talk – Gustavo H. C. Varca

Country/Organization

Brazil

Type

scientific paper

Year

2013

Description

DIBA BEHNOODFAR1, SUSAN DADBIN2, and MASOUD FROUNCHI, PLA Microspheres-Embedded PVA Hydrogels Prepared by Gamma-irradiation and Freeze-Thaw Methods as Drug Release Carriers, International Journal of Polymeric Materials 2013, 62, 28-33.

Country/Organization

Iran

Type

scientific paper

Year

2010

Description

J. Chen, D. Li, H. Koshikawa, M. Asano, and Y. Maekawa, “Crosslinking and grafting of polyetheretherketone film by radiation techniques for application in fuel cells”, J. Membr. Sci., 362, 488-494 (2010)

Country/Organization

Japan

Type

scientific meeting contribution

Year

2011

Description

Spasojevic, J., Krstic, J., Radosavljevic, A., Kalagasidis-Krusic, M., Kacarevic-Popovic, Z., “Thermoresponsive silver/poly(N-isopropylacrylamide) hydrogel nanocomposites synthesized by gamma irradiation”, Tenth Young Researchers Conference - Materials Science and Engineering, Serbian Academy of Sciences and Arts (SASA), Belgrade, Serbia, December 21-23, 2011, Program and the Book of Abstracts, XI/2, p.44

Country/Organization

Serbia

Type

scientific conference contribution

Year

2010

Description

QUIROGA F. Y., GRASSELLI M.; Modificación superficial de HDPE con injertos catiónicos para la adsorción de microorganismos. Aplicaciones en el área de biocatálisis. I° Simposio Argentino de los Procesos Biotecnológicos. Rosario, Argentina, 25 November 2010.

Country/Organization

Argentina

Type

scientific paper

Year

2009

Description

BARSBAY, M., GÜVEN, O., “A Short review of radiation-induced RAFT-mediated Graft Copolymerization” Rad. Phys. Chem., 78(2009)1054-1059.

Country/Organization

Turkey

Type

scientific conference contribution

Year

2010

Description

CVETICANIN, J., KRKLJES, A., KACAREVIC-POPOVIC, Z., TRPKOV, DJ., CINDRIC, M., NESKOVIC, O., „Mass Spectrometric Investigation of Silver Clusters“, 10th International Conference of Fundamental and Applied Aspects of Physical Chemistry, PHYSICAL CHEMISTRY 2010, September 21-24, 2010, Belgrade, Serbia, Proceedings, p.60-62.

Country/Organization

Serbia

Type

scientific paper

Year

2011

Description

S. Sawada and Y. Maekawa, “Proton Conduction Characteristics in Radiation-Grafted Polymer Electrolyte Membranes Based on Perfluorinated and Aromatic Hydrocarbon Polymers”, ECS Trans., 41, 2125-2133 (2011)

Country/Organization

Japan

Type

scientific meeting contribution

Year

2012

Description

Dadbin S, Naimian F. Kheirkhah Y. PLA/clay nanocomposites: Effects of preparation method on morphology and mechanical properties, ISPST2012, Amirkabir University of Technology, Tehran, Iran, 21-25 October 2012

Country/Organization

Iran

Type

scientific paper

Year

2009

Description

BARSBAY, M., GÜVEN, O., DAVIS, T. P., BARNER-KOWOLLIK, C., BARNER, L., “RAFT-mediated polymerization and grafting of 4-styrenesulfonate from cellulose initiated via gamma-radiation” Polymer, 50(2009)973-982.

Country/Organization

Turkey

Type

scientific paper

Year

2010

Description

JOVANOVIC, Z., KRKLJES, A., TOMIC, S., MISKOVIC-STANKOVIC, V., POPOVIC, S., DRAGASEVIC, M., KACAREVIC-POPOVIC, Z., “Properties of Ag/PVP Hydrogel Nanocomposite Synthesized In Situ by Gamma Irradiation”, in Trends in Nanophysics: Theory,Experiment and Technology. Eds: Alexandru Aldea, Victor Bârsan. Springer-Verlag Berlin Heidelberg, 2010, 315-328.

Country/Organization

Serbia

Type

scientific meeting contribution

Year

2009

Description

Dispenza, M. Ricca, C. Lo Presti, G. Spadaro, A. Blanazs, G. Battaglia “Biocompatible nanostructured hydrogels incorporating polyaniline nanoparticles” Frontiers in Polymer Science Mainz 7-9 June 2009, Germany. P3-58.

Country/Organization

Italy

Type

scientific paper

Year

2011

Description

AKBULUT, M., LAKSHMI, D., WHITCOMBE, M.J., PILETSKA, E., CHIANELLA, I., GÜVEN, O., PLETSKY,S., “Microplates with Adaptive Surfaces” ACS Combinatorial Science, 13(2011)646-652.

Country/Organization

Turkey

Type

scientific paper

Description

BARSBAY, M., GUVEN, O., BESSBOUSSE, H., WADE, T.L., CLOCHARD M-C., Nanopore size tuning of polymeric membranes using the RAFT-mediated radical polymerization, J. Memb. Sci. (submitted)

Country/Organization

France - Turkey

Type

scientific conference contribution

Year

2011

Description

MISRA, N., BISWAL, J., SABHARWAL, S.; Synthesis of polyvinylpyrrolidone stabilized gold nanoparticles by gamma irradiation, NSRP, JNV Univ., Jodhpur, Rajasthan, India, 10-12, March 2011.

Country/Organization

India

Type

scientific conference contribution

Year

2010

Description

KACAREVIC-POPOVIC, Z., DRAGASEVIC, M., KRKLJES, A., POPOVIC, S., JOVANOVIC, Z., TOMIC, S., MISKOVIC-STANKOVIC, V., „On the Use of Radiation Techology for Nanoscale Engineering of Silver/Hydrogel Based Nanocomposites for Potential Biomedical Application“, 2nd International Conference on Drug Discovery and Therapy, Dubai Men‘s College, Dubai, United Arab Emirates, February 1-4, 2010, Abstracts, SL-319, p.117

Country/Organization

Serbia

Type

scientific conference contribution

Year

2012

Description

SOTO ESPINOZA, S. L., GRASSELLI, M.; Synthesis and modification of cylindrical and conical nanopores on track-etched membranes, VIII Congreso Iberoamericano en Ciencia y Tecnología de membranas. Salta, Argentina, 24 - 27 April 2012.

Country/Organization

argentina

Type

scientific paper

Year

2011

Description

JOVANOVIC, Z., KRKLJES, A., STOJKOVSKA, J., TOMIC, S., OBRADOVIC, B., MISKOVIC-STANKOVIC, V., KACAREVIC-POPOVIC, Z., “Synthesis and characterization of Ag/PVP hydrogel nanocomposite obtained by in situ radiolytic method”, Rad. Phys. Chem. 80 (2011) 1208-1215.

Country/Organization

Serbia

Type

scientific meeting contribution

Year

2012

Description

IAEA Arcal CVIII – São Paulo, Brazil. (2012) “Advances in the use of radiation Technology and nanotechnology in tissue engineering” – Invited Talk – “Nanotecnología aplicada a la salud” - Gustavo H.C. Varca

Country/Organization

Brazil

Type

scientific paper

Year

2010

Description

Ricca, V. Foderà, D. Giacomazza, M. Leone, G. Spadaro, C. Dispenza “Probing the internal environment of PVP networks generated by irradiation with different sources” Colloid Polym. Sci. 288 (2010) 969 980.

Country/Organization

Italy

Type

scientific paper

Year

2010

Description

S. Sawada, A. Suzuki, T. Terai and Y. Maekawa, “TEMPO addition into pre-irradiated fluoropolymers and living-radical graft polymerization of styrene for preparation of polymer electrolyte membranes, “, Radiat. Phys. Chem., 79, 471-478 (2010)

Country/Organization

Japan

Type

scientific paper

Year

2010

Description

K. Enomoto, Y. Maekawa, S. Takano, M. Iwasaki and T. Narita, “Electron-beam-induced chromism combined with photo- or thermal reverse reaction for color imaging“, J. Photopolym. Sci. Technol., 23, 217-224 (2010)

Country/Organization

Japan

Type

scientific paper

Description

Soto Espinoza, S. L., Arbeitman, C. R., Clochard, M.C., Grasselli M., Functionalization of nanochannels by radiation-induced grafting polymerization on PET track-etched membranes, Rad. Phys. Chem. (submitted).

Country/Organization

France - Argentina

Type

scientific conference contribution

Year

2012

Description

10th Ionizing Radiation and Polymer Symposium – Krakow, Poland. (2012) Oral Presentation - “Radio-synthesized papain nanoparticles for biomedical purposes” - Varca, G.H.C; Ferraz, C. C.; Lopes, P; S.; Grasselli, M.; Lugão, A.B.

Country/Organization

Brazil-Argentina

Type

scientific paper

Year

2012

Description

OLIANI W.L, PARRA D.F., RIELLA H.G., LIMA L.F.C.P., LUGAO A.B.. Polypropylene nanogel: “Myth or reality”. Radiation Physics and Chemistry, Volume 81, Issue 9, September 2012, Pages 1460-146.

Country/Organization

Brazil

Type

scientific paper

Year

2011

Description

H. Iwase, S. Sawada, T. Yamaki, Y. Maekawa and S. Koizumi, “Preirradiation graft polymerization of styrene in a poly(tetrafluoroethylene) film, investigated by time-resolved small-angle neutron scattering “, Int. J. Polym. Sci., 2011, 301807 (2011).

Country/Organization

Japan

Type

scientific conference contribution

Year

2011

Description

MISRA, N., BISWAL, J. DHAMGAYE, V. LODHA, G. S., SABHARWAL, S.; Synthesis of silver nanoparticles by using synchrotron radiation at INDUS II, ETALAN, TSH, Mumbai, India, 20-21 October 2011.

Country/Organization

India

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