Slide 7 of 49
Notes:
Residue analysis is an extremely challenging task. Practical and robust analytical methods capable of extracting the analyte from complex biological matrices, such as bile, liver, kidney and faeces, and purifying that extract to enable detection of the analyte at these levels are essential.
The challenge of residues analysis must not be underestimated. Tissues such as bile, faeces, liver and kidney are extremely complex biological matrices from which trace levels (typically between 1 part in a billion to 1 part in a million) of drugs and metabolites must be extracted. Purification to achieve detection at these levels is essential. Sophisticated equipment may be needed to identify and quantify the particular drug residue present in the sample.