|
|
uric acid + O2 = allantoin + unidentified products
The enzyme is highly specific.
View
the reaction (using 15N labeled uric acid as the substrate)
Purine
degradation pathway
 |
Commercial products are usually derived from porcine liver, ox kidney |
|
Optimum pH: 8.5-10.5 |
|
Michaelis constant: 1.73 x 10-5 |
|
Inhibitors: |
Distribution in animal tissues
There are few reports on the tissue distribution of uricase in animals.
In the blood of ruminants, uricase is either not present or is low in activity.
){kind=link}
){kind=link}